Fundamentals Of Power Supply Design Robert A. 32.epub: How to Create Reliable and Efficient Power Su

The optimal method for replacing fibrinogen in traumatic haemorrhage is fiercely debated. In this trial the feasibility and efficacy of fibrinogen supplementation using FC will be compared to Cryo. The results of this pilot study will facilitate the design of a larger trial with sufficient power to address patient-centred outcomes.

To our knowledge, FEISTY is the first RCT comparing FC to Cryo for fibrinogen supplementation in severe traumatic haemorrhage. The trial expands on the currently utilised VHA-guided approach at the study sites, with fibrinogen supplementation and dosing guided by FIBTEM analysis [72]. In addition to assessing the differential time to effective fibrinogen supplementation, this trial will provide information on appropriate dosing of fibrinogen in traumatic haemorrhage. The results of this pilot trial in conjunction with other ongoing trials will be used to design a larger trial powered to address patient-centred outcomes such as blood product transfusion requirements and mortality.

Fundamentals Of Power Supply Design Robert A. 32.epub

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